A dual purpose antideath agent

Recent Advances in PET-MR Hybrid contrast agent

Introduction: All of the Imaging modalities have advantages and disadvantages alone. So if we want to have the best and perfect image, combining these modalities produces something we desired. PET-MR images consist of morphologic and metabolic data. MRI and PET provide high spatial and contrast resolution and high sensitivity and molecular information respectively. Hybrid PET-...

ارزیابی میزان دقت جداسازی تصاویر دو ماده حاجب مختلف به صورت همزمان از بافت پستان با استفاده از تکنیک ماموگرافی دیجیتال دو انرژی

Background and purpose: Dual-energy mammography is a technique which is used to enhance the accuracy of breast cancer diagnosis especially in dense breasts. This study was conducted based on the simultaneous use of two contrast agents for automatic separation and also to evaluate their accuracy using dual-energy digital mammography. Materials and methods: A breast phantom was designed and b...

Dual-Target Anticancer Drug Candidates: Rational Design and Simulation Studies

This study aims to design some dual-target anticancer candidates, capable to act as an alkylating agent as well as a thymidylate synthase (TS) inhibitor. The designed scaffold is a combination of nucleobase, amino acid and aziridine structures. The candidates are docked into TS and three DNA double strand structures and evaluated based on their binding interaction energies and ligand efficienci...

Preparation of a Dual-Purpose Cell Culture Mumps Virus Antigen for HI and CF Tests

Use of laser-triggered gold nanoparticle-grafted dual light and temperature-responsive polymeric sensor for the recognition of thioguanine as anti-tumor agent

Objective(s): Today, there is an urgent need for improved sensor materials for drug sensing and effective monitoring and interventions in this area are highly required to struggle drug abuse. The present study aimed to synthesize a thioguanine-responsive sensor based on a nanocomposite consisting of AuNP-grafted light- and temperature-responsive poly butylmethacrylate-co-acrylamide-co-methacryl...